Analysis of the Article
1. Core Topic & User Question:
The article discusses a new study that sheds light on why women experience Irritable Bowel Syndrome (IBS) at a significantly higher rate than men. It identifies a specific mechanism involving estrogen, gut cells, and serotonin release that contributes to increased pain sensitivity in the female digestive system. The user question it’s answering is essentially: “Why are women more susceptible to IBS?” or “What causes the gender disparity in IBS cases?”.
2. Optimal Keywords:
* Primary Topic: Irritable Bowel Syndrome (IBS) & Gender Differences
* Primary Keyword: IBS in women
* Secondary Keywords:
* Estrogen
* Gut microbiome
* Serotonin
* PYY (Peptide YY)
* OLFR78 (Olfactory Receptor 78)
* visceral pain
* Hormonal influence on IBS
* Gut-brain axis
* Women’s health
* Digestive health
* Inflammatory bowel syndrome (IBS)
* Gut cells
* Hormone receptors
* Pain sensitivity
* Irritable bowel syndrome research
* Gut hormone
* cell-L
* Acid fatty chain
* Menstrual cycle
* Gut health
