Multiple myeloma, a cancer originating in plasma cells, is a meaningful health concern, especially affecting men at a higher rate than women.Recent investigations have begun to unravel the complexities behind this disparity, pinpointing several clinical characteristics that may contribute to the increased risk observed in males.
Currently, multiple myeloma ranks as the second most prevalent blood cancer in the United States, and its incidence is steadily rising. According to the American Cancer Society, an estimated 35,730 new cases will be diagnosed in 2026 . understanding the factors driving this increase, including sex-specific differences, is crucial for improved prevention and treatment strategies
