Navigating Opioid Safety in Cancer Care: A Comprehensive Approach to Stewardship
The responsible management of opioid pain medication is a critical concern across healthcare, but presents unique challenges within oncology. Cancer patients often experience severe, complex pain requiring robust treatment, yet are together vulnerable to opioid misuse, abuse, and diversion. This article details the crucial role of opioid stewardship programs – and the interdisciplinary teams driving them – in balancing effective pain management with patient safety, drawing on insights from the opioid stewardship programme at MD Anderson Cancer Center.
The Growing Need for Opioid Stewardship in Oncology
For years, healthcare providers have recognized the potential for harm associated with opioid prescribing. However,the complexities of cancer care necessitate a nuanced approach. Unlike typical chronic pain settings, dismissing patients for non-adherence isn’t a viable option. Cancer patients require pain management to maintain quality of life,even while struggling with substance use or exhibiting risky opioid behaviors.
“The challenge is that even if patients misuse their opioids, use illicit substances, divert, or take more than prescribed, they still have cancer,” explains Matthew D. Clark, PharmD, a pharmacist specializing in pain management and palliative care at MD Anderson. “that means they will still have pain and symptoms related to cancer.”
This reality underscores the need for proactive, comprehensive opioid stewardship programs – a framework for opioid safety that extends beyond simply identifying misuse. These programs aim to optimize opioid use, minimize harm, and provide compassionate care to a vulnerable population.
The Interdisciplinary Team: A Cornerstone of Effective Stewardship
Successful opioid stewardship isn’t a solo effort. It requires a collaborative, interdisciplinary team working in concert. MD Anderson’s program exemplifies this approach, built around a core team of:
* Medical Director: Provides overall clinical leadership and ensures alignment with institutional goals.
* Nurse Practitioner: Plays a vital role in patient assessment, monitoring, and developing individualized treatment plans. Early identification of concerning patterns – like frequent early refill requests – frequently enough originates with nursing staff.
* pharmacist (Opioid Stewardship Specialist): Serves as the central point for opioid safety monitoring and intervention. This role is multifaceted, encompassing:
* Urine Drug screening (UDS) Management: Randomizing, interpreting UDS results, and correlating findings with patient reports and prescribed regimens. Discrepancies (e.g., no opioids detected despite reported adherence, presence of illicit substances) trigger further investigation.
* Prescription Drug Monitoring Program (PDMP) Review: Identifying “doctor shopping” or “pharmacy shopping” behaviors – seeking prescriptions from multiple providers or pharmacies – to prevent oversupply and potential diversion.
* treatment Plan Development: Collaborating with the team to adjust opioid regimens, implement closer monitoring, or initiate supportive interventions.
* Clinical Pharmacy Services: Providing standard pharmacist duties like medication education, reconciliation, and ongoing clinical support in pain management and palliative care.
Beyond this core team, crucial support comes from:
* Psychosocial Counseling: Addressing underlying psychological factors contributing to opioid misuse, providing coping strategies, and offering behavioral therapy.
* social Work: Connecting patients with resources to address social determinants of health that may impact opioid use, such as housing instability or financial hardship.
* Case Management: coordinating care and ensuring patients have access to necessary support services.
Addressing Unique Challenges in Cancer Care
Opioid stewardship programs in cancer centers must navigate specific hurdles:
* Complex Pain Syndromes: Cancer pain is frequently enough multifaceted, requiring individualized treatment plans that may involve multiple medications and modalities.
* Vulnerability to Misuse: Patients facing a life-threatening illness may be more susceptible to developing problematic opioid use patterns.
* The Imperative of Pain Control: Unlike many chronic pain settings, discontinuing opioid therapy is rarely an option due to the ongoing need for symptom management.
MD Anderson’s program addresses these challenges by prioritizing continuity of care. When non-medical opioid use is identified, patients are transitioned to a dedicated team that assumes duty for their opioid prescribing and monitoring.
“What we’ve found is that once patients experience continuity-seeing the same provider, the same pharmacist, the same counselor-their behaviors improve,” clark explains. “That continuity has decreased risky behaviors, and that’s something we pride ourselves on and continue to provide to the institution.”
This approach typically involves:
* Frequent Follow-Ups: Weekly visits are scheduled for patients exhibiting active misuse or substance use, gradually transitioning to monthly visits as adherence and abstinence are demonstrated.
* Individualized Treatment Plans: Adjusting opioid dosages, exploring alternative pain management strategies, and providing ongoing support.
* rare Dismissal: Dismissal to community care is reserved for cases of persistent non-adherence or continued substance abuse,and is uncommon.
Looking Ahead: The Future of Opioid Stewardship in Oncology
Opioid stewardship is an evolving field. Future directions include:








