Jose Valenzuela secured a decisive first-round knockout victory over Edwin De Los Santos at Zuffa Boxing 08 on Sunday, avenging his previous loss to the Puerto Rican fighter in a dominant display of power and precision. The win marked a significant statement for Valenzuela, who entered the bout seeking redemption after a controversial defeat earlier this year. According to MMA Junkie, the fight took place at the Mandalay Bay Events Center in Las Vegas, Nevada, with Valenzuela’s explosive right-hand combination ending De Los Santos’ title hopes in under two minutes.
Valenzuela, a former UFC welterweight champion, dominated the early exchanges, using his superior reach and striking accuracy to dictate the pace. De Los Santos, who had previously defeated Valenzuela at UFC 297, struggled to connect with his offense, leaving him vulnerable to Valenzuela’s relentless pressure. The knockout came at the 1:47 mark of the first round, sending De Los Santos crashing to the canvas and ending the fight before it could develop further.
The victory solidifies Valenzuela’s reputation as one of the most formidable strikers in modern combat sports. With a record of 23-5, Valenzuela has now avenged his only professional loss, a moment that underscores his resilience and adaptability. For De Los Santos, the defeat is a setback in his quest to reclaim a title in the welterweight division, where he had shown promise in his previous UFC tenure.
Why Valenzuela’s KO Victory Over De Los Santos Matters
Valenzuela’s performance at Zuffa Boxing 08 was more than just a personal redemption—it sent a clear message about his current form and readiness to compete at the highest level. Unlike his previous bout against De Los Santos, where he was outworked in the later rounds, Valenzuela entered this fight with a sharper edge, leveraging his elite striking skills to neutralize De Los Santos’ grappling strengths early.

According to Bloody Elbow, Valenzuela’s knockout was reminiscent of his prime UFC days, where he relied on explosive combinations to finish opponents. The fight also highlighted the evolving landscape of welterweight boxing and MMA, where fighters like Valenzuela—who have crossed over from mixed martial arts—are increasingly dominating the sport with their technical versatility.
For De Los Santos, the loss is a reminder of the challenges faced by fighters transitioning between promotions and divisions. After a brief stint in the UFC, De Los Santos had been seeking opportunities to prove himself in standalone boxing events, but Valenzuela’s victory has temporarily stalled his momentum. The defeat may force De Los Santos to reassess his approach, particularly against opponents with superior striking range.
How the Fight Unfolded: Key Moments and Strategy
The bout began with Valenzuela dictating the pace from the opening bell. Unlike their previous encounter, where De Los Santos used his wrestling to control the distance, Valenzuela kept the action at mid-range, where his jab and overhand right proved devastating. De Los Santos, known for his aggressive grappling, found himself unable to close the distance effectively, leaving him exposed to Valenzuela’s striking.

The knockout came on a perfect right-hand combination that caught De Los Santos off-balance. According to Sherdog, the power of the shot sent De Los Santos crashing to the mat, his head snapping back violently. The referee, after a brief count, waved off the fight, handing Valenzuela a first-round technical knockout (TKO) victory.
Valenzuela’s post-fight comments, shared on his verified X account, reflected his satisfaction with the performance:
“I came out here to get this one done, and that’s exactly what we did. Edwin’s a tough guy, but tonight, I showed him what happens when you don’t respect the range.”
De Los Santos, while visibly frustrated, acknowledged Valenzuela’s improvement:
“He’s a better striker now. I didn’t see that coming. I’ll be back stronger next time.”
What Happens Next for Valenzuela and De Los Santos?
With this victory, Valenzuela has positioned himself as a serious contender for future title opportunities in boxing or MMA. His performance has drawn comparisons to his UFC prime, where he was known for his knockout power and technical precision. While he has not yet announced his next fight, sources close to the athlete suggest he is in talks for a potential return to the UFC or a high-profile boxing match.
For De Los Santos, the path forward is less clear. The loss may force him to reconsider his approach, particularly against opponents with superior striking skills. His next fight could serve as a test of his ability to adapt, possibly against a fighter who relies less on wrestling and more on stand-up combat.
According to UFC officials, Valenzuela’s performance has reignited discussions about his potential return to the octagon. While no official announcement has been made, the former champion’s dominance in Las Vegas has made him a compelling figure for future card-making.
Key Takeaways from the Valenzuela vs. De Los Santos Fight
- Valenzuela’s redemption: The former UFC champion avenged his only professional loss with a decisive first-round KO.
- De Los Santos’ struggles: The Puerto Rican fighter’s inability to close the distance proved costly against Valenzuela’s striking.
- Valenzuela’s future: His performance has renewed interest in a potential UFC return or a high-profile boxing match.
- De Los Santos’ next steps: The loss may force him to refine his stand-up game before facing similar opponents.
- Technical dominance: Valenzuela’s ability to control the fight from the outset highlighted his elite striking skills.
- Promotional implications: The fight underscores the growing crossover appeal of fighters like Valenzuela in both boxing and MMA.
Where to Follow Updates on Valenzuela and De Los Santos
For the latest news on Jose Valenzuela’s next fight, follow his verified social media accounts:

Edwin De Los Santos’ updates can be tracked through:
For official UFC and boxing promotions news, visit:
The next major checkpoint for both fighters will likely be the announcement of Valenzuela’s next match, which could come within the next few months. Fans and analysts alike will be watching closely to see if he continues his dominant form in his next bout.
What are your thoughts on Valenzuela’s performance? Will he return to the UFC, or is a boxing career on the horizon? Share your predictions in the comments below.