Puerto Rico has recorded a dramatic surge in Zika virus infections in 2024, with health officials confirming over 5,500 cases reported since January, including 672 infections among pregnant women, according to the latest data from the U.S. Centers for Disease Control and Prevention (CDC) and Puerto Rico’s Department of Health. The outbreak, which has raised alarms among public health experts, comes as the territory grapples with mosquito-borne disease resurgence after years of relative control. The CDC has issued updated travel advisories, while local authorities are scaling up vector control efforts amid concerns about congenital Zika syndrome and long-term neurological complications.
Zika virus, primarily transmitted through Aedes aegypti and Aedes albopictus mosquitoes, has re-emerged as a significant public health threat in Puerto Rico following a lull in reported cases after the 2015–2016 epidemic. The latest figures mark a near-tripling of infections compared to the same period last year, prompting the CDC to elevate its travel health notice for Puerto Rico from “Level 1: Practice Usual Precautions” to “Level 2: Practice Enhanced Precautions” for pregnant women and those planning to become pregnant.
Dr. Carmen Deseda, Secretary of the Puerto Rico Department of Health, stated in a recent press release that the territory is “experiencing an unprecedented rise in Zika cases,” attributing the spike to increased mosquito populations due to recent heavy rainfall and inadequate vector control in certain regions. “We are working closely with the CDC and local municipalities to intensify surveillance, testing, and mosquito abatement efforts,” Deseda added. The department has also launched a public awareness campaign targeting pregnant women, emphasizing the risks of congenital Zika syndrome, which includes severe birth defects such as microcephaly and other neurological complications.
Why the surge matters: A closer look at the risks
What’s driving the Zika resurgence in Puerto Rico?
Public health officials point to three primary factors behind the recent spike in Zika cases:

- Climate conditions: Puerto Rico has faced above-average rainfall in 2024, creating ideal breeding grounds for Aedes mosquitoes. The CDC notes that even small amounts of stagnant water—such as in discarded containers or clogged gutters—can support mosquito populations.
- Reduced vector control: Funding cuts to mosquito control programs in some municipalities have led to gaps in larvicide distribution and adulticide spraying, according to a recent report by the Puerto Rico Legislative Commission on Public Health. The territory’s Department of Agriculture has reported a 20% increase in mosquito traps testing positive for Aedes aegypti in high-risk zones.
- Diagnostic challenges: Zika often presents with mild or non-specific symptoms, such as fever, rash, and joint pain, which can lead to underreporting. The CDC has recently updated testing guidelines to encourage healthcare providers to order Zika testing for patients with compatible symptoms, particularly in pregnant women.
The resurgence follows a declining trend in Zika cases between 2017 and 2022, during which Puerto Rico reported fewer than 50 cases annually. Health experts caution that the current outbreak may not be isolated to the territory, given the mosquito’s established presence in the Caribbean and southern U.S..
Who is most at risk—and what are the health consequences?
While Zika can infect anyone, certain groups face higher risks of severe outcomes:

- Pregnant women: Infection during pregnancy can cause congenital Zika syndrome, which includes microcephaly, vision and hearing loss, and developmental delays. The CDC recommends that pregnant women in Puerto Rico avoid travel to high-risk areas and take precautions such as wearing long sleeves, using EPA-approved repellents, and eliminating standing water.
- Newborns and infants: Babies born to infected mothers may require long-term monitoring for developmental issues. The Puerto Rico Department of Health has expanded pediatric surveillance to track potential cases of congenital Zika syndrome.
- Individuals with weakened immune systems: While rare, Zika has been linked to Guillain-Barré syndrome and other neurological complications in immunocompromised patients.
For the general population, Zika typically causes mild illness, but about 1 in 5 people infected may develop symptoms. The virus can also be transmitted through sex, though this is less common than mosquito-borne transmission.
How is Puerto Rico responding—and what can travelers do?
The Puerto Rico government and CDC are implementing a multi-pronged response:

- Enhanced surveillance: The Department of Health has increased testing capacity in high-risk regions, including San Juan, Ponce, and Mayagüez, where mosquito populations are densest.
- Mosquito control: Teams are conducting door-to-door inspections to eliminate breeding sites, while aerial spraying of larvicides is being expanded in affected areas.
- Public education: Health officials are collaborating with local media to disseminate prevention messages, including the use of permethrin-treated clothing and bed nets for high-risk individuals.
- Travel advisories: The CDC advises pregnant women to avoid nonessential travel to Puerto Rico unless they take strict precautions. Non-pregnant travelers should still protect against mosquito bites, particularly during dawn and dusk.
Dr. Ana Velez, an infectious disease specialist at the University of Puerto Rico Medical Sciences Campus, emphasized the importance of community involvement. “This is not just a government issue—it’s a collective effort,” she told World Today Journal. “Residents must eliminate standing water, report mosquito sightings, and use repellents consistently. Small actions can make a big difference in stopping the spread.”
What happens next: Monitoring and long-term risks
The CDC’s Zika response team will continue to collaborate with Puerto Rico’s health authorities to assess the outbreak’s trajectory. Key next steps include:
- Weekly case reporting: The CDC and Puerto Rico Department of Health will publish updated case counts biweekly in the Morbidity and Mortality Weekly Report (MMWR).
- Vaccine research: While no Zika vaccine is currently approved, the CDC is monitoring clinical trials for potential candidates, including those led by the National Institutes of Health (NIH).
- Regional coordination: The Pan American Health Organization (PAHO) is working with Caribbean nations to share best practices for mosquito control and surveillance.
The next critical checkpoint will be the August 9 release of the MMWR, which will provide updated case data and assess whether the outbreak is stabilizing or worsening. In the meantime, health officials urge residents and travelers to remain vigilant.
Key resources for travelers and residents
For the latest updates and safety guidance, consult these authoritative sources:
- CDC Travel Health Notice for Puerto Rico
- Puerto Rico Department of Health Epidemiological Bulletin
- PAHO Zika Virus Resources
- EPA-Approved Mosquito Repellents
Puerto Rico’s Zika outbreak serves as a reminder of the ongoing threat posed by mosquito-borne diseases in tropical and subtropical regions. As climate change expands the range of Aedes mosquitoes, public health agencies are bracing for potential future surges. For now, prevention remains the most effective tool—whether you’re a resident, a traveler, or a pregnant woman planning a trip.
Have questions about Zika prevention or the latest outbreak? Share your concerns in the comments below, and stay tuned for further updates as the situation develops.