The pursuit of weight loss has led many to explore medications like Ozempic and Wegovy, alongside older options such as Orlistat and Fenfluramin.Increasingly, individuals are turning to these drugs to achieve their desired weight. Recent data from a report released in early 2026 indicates that the use of weight loss medications in Germany has roughly doubled between 2020 and 2024.
Initial results often appear promising, but a recent extensive analysis conducted by researchers at the University of Oxford reveals a concerning trend. Typically, weight regain occurs rapidly after discontinuing these medications-even faster than after following traditional diet and exercise programs.
The Oxford study, published in the British Medical Journal, analyzed data from 37 studies encompassing 9,341 adults who were overweight or living with obesity. Participants received a weight reduction medication for an average of 39 weeks, including modern GLP-1 receptor agonists like Semaglutide (found in Ozempic and Wegovy), Liraglutide (Saxenda), and Tirzepatide (Mounjaro). Following medication cessation, participants were monitored
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